Caris Life Sciences

Caris’ Precision Oncology Alliance Welcomes Tampa General Hospital Cancer Institute

March 2, 2022 Published by Roboticulized.com

Caris Life Sciences^®(Caris), the leading molecular science and technology company actively developing and delivering innovative solutions to revolutionize health care, announced today that Tampa General Hospital Cancer Institute (TGH Cancer Institute) has joined Caris’ Precision Oncology Alliance (POA). The POA is a growing network of leading cancer centers across the globe that collaborate to advance precision oncology and biomarker-driven research. POA members work together to establish and optimize standards of care for molecular testing through innovative research focused on predictive and prognostic markers that improve the clinical outcomes for cancer patients.

Established in 2021 and building on the success of the Tampa General Hospital oncology program, the TGH Cancer Institute provides comprehensive care via state-of-the-art therapies and advanced diagnostic imaging and molecular tools. As part of an academic medical center, TGH Cancer Institute’s team of surgical, medical and radiation oncologists, together with other medical specialists, take a multidisciplinary approach, combining access to cutting-edge clinical trials and therapies with compassionate and personalized care focusing on the whole patient. TGH Cancer Institute is rated among the top 10% of U.S. hospitals for cancer care, according to U.S. News & World Report‘s 2021-2022 rankings.

“TGH Cancer Institute is thrilled to join the Caris Precision Oncology Alliance and partner with key academic and clinical institutions similarly dedicated to advancing precision medicine and biomarker research,” said Eduardo M. Sotomayor, M.D., Director, TGH Cancer Institute. “Our goal is to bring world-class, leading-edge and innovative cancer care to the Tampa Bay region, and the POA offers our team access to a collaborative research network focused on identifying predictive and prognostic markers. As a physician-scientist myself, I know that access to advanced research and innovations make a significant impact in improving the outcomes and clinical care of patients with cancer.”

TGH Cancer Institute’s nationally renowned cancer physicians and physician-scientists offer a highly coordinated range of multidisciplinary specialties such as hematologic malignancies, neuro-oncology, thoracic, breast, colorectal, urologic, head and neck and gynecologic oncology.

“TGH Cancer Institute’s focus on innovation and research builds upon the POA’s goal to promote broad-based collaboration among our member institutions in precision oncology research to improve outcomes of all patients with cancer,” said Chadi Nabhan, M.D., MBA, FACP, Chairman of the Caris Precision Oncology Alliance. “We are excited to welcome them to the POA, and look forward to helping them advance cancer care in the region.”

“Partnering with Caris will not only allow us to integrate state-of-the-art somatic tumor profiling for more precise diagnosis and treatment into clinical care, but also elevate the functionality of our rapidly growing biorepository and other core resources,” said Matthew L. Anderson, M.D., Ph.D., Associate Director for Shared Resources, TGH Cancer Institute and Professor in the Department of Obstetrics and Gynecology for the USF Health Morsani College of Medicine. “Access to molecularly characterized specimens will be a powerful tool we intend to leverage as we grow our translational and basic research portfolio.”

In addition to serving the greater Tampa Bay region on the west coast of Florida, Tampa General is bringing together a network of cancer services to link patients on Florida’s east coast to highly complex care. Patients in the Palm Beach and Treasure Coast area can receive care in their own community and when needed, access Tampa General for advanced treatment and services.

“Joining the POA will provide the TGH Cancer Institute with broader resources, and bring groundbreaking cancer care to patients on both the east and west coast of Florida,” said Abraham Schwarzberg, M.D., Chief of Oncology and Senior Vice President of Network Development, Tampa General. “This is exactly the type of alliance that will help us move forward in our vision to be the safest and most innovative academic health system in America.”

The Caris Precision Oncology Alliance includes 59 cancer centers and academic institutions. These institutions have early access to the extensive database and artificial intelligence platform within Caris to establish evidence-based standards for cancer profiling and molecular testing in oncology. By leveraging the comprehensive genomic, transcriptomic and proteomic profiling available through Caris molecular profiling, Caris seeks to provide this network with the ability to prioritize therapeutic options and determine which clinical trial opportunities may benefit their patients. POA members are also able to integrate with a growing portfolio of biomarker directed trials sponsored by biopharma. Additionally, as a member of the POA, institutions have access to Caris CODEai, the most comprehensive data solution in the industry with cancer treatment information and clinical outcomes data for over 275,000 patients covering over 1 million data points per patient.

Caris Life Sciences Announces Appointment of Lloyd B. Minor to Board of Directors

November 19, 2021 Published by Roboticulized.com

Caris Life Sciences^®(Caris), the leading molecular science and technology company actively developing and delivering innovative solutions to revolutionize healthcare, announced today the appointment of Lloyd B. Minor, M.D. to the Caris Board of Directors, effective immediately. Following the appointment of Dr. Minor, the Board will be comprised of 11 directors.

The Caris Life Sciences Board is composed of a diverse group of leaders with distinct perspectives. Many of the current directors have held leadership roles at major domestic and international companies, academic and scientific organizations, and governmental agencies.

“We are excited to welcome Dr. Minor to the Caris Board,” said David D. Halbert, Chairman and CEO of Caris Life Sciences. “Dr. Minor’s combined expertise in academia and science has established him as a leading advocate for innovation in the field of precision healthcare and his perspectives will be invaluable as we reinvent the way medicine is practiced, and pursue our vision to improve patient outcomes across all disease types worldwide.”

“I am pleased to join the Caris Board, and welcome the opportunity to contribute to Caris’ future growth and success as the company advances innovative technologies,” said Dr. Minor. “I look forward to working alongside fellow board members, and Caris’ management team, to collectively revolutionize patient care.”

Lloyd B. Minor, M.D., is a scientist, surgeon and academic leader. He is the Carl and Elizabeth Naumann Dean of the Stanford University School of Medicine, a position he has held since December 2012. As dean, Dr. Minor plays an integral role in setting strategy for the clinical enterprise of Stanford Medicine, an academic medical center that includes the Stanford University School of Medicine, Stanford Health Care, and Stanford Children’s Health and Lucile Packard Children’s Hospital Stanford. He also oversees the quality of Stanford Medicine’s physician practices and growing clinical networks. An advocate for innovation, Dr. Minor has provided significant support for fundamental science and for clinical and translational research at Stanford. Through bold initiatives in medical education and increased support for Ph.D. students, Dr. Minor is committed to inspiring and training future leaders. Before coming to Stanford, Dr. Minor was provost and senior vice president for academic affairs of The Johns Hopkins University. During his time as provost, Dr. Minor launched many university-wide initiatives such as the Gateway Sciences Initiative to support pedagogical innovation, and the Doctor of Philosophy Board to promote excellence in Ph.D. education. He worked with others around the university and health system to coordinate the Individualized Health Initiative, which aimed to use genetic information to transform health care. In 2012, Dr. Minor was elected to the National Academy of Medicine, formerly the Institute of Medicine.

Caris Life Sciences Announces Appointment of Mike Weinstein, Medical Technology Executive and Wall Street Veteran, as Chief Financial Officer

October 7, 2021 Published by Roboticulized.com

Caris Life Sciences®, a molecular science company developing and delivering technologies to revolutionize healthcare, announced today the appointment of Mike Weinstein as Executive Vice President and Chief Financial Officer.

“We are thrilled to welcome Mike to the Caris team,” said David D. Halbert, Chairman and CEO of Caris Life Sciences. “His passion for our mission, industry experience and strategic thinking will provide strong leadership as we position Caris for the next phase; expanding our offering to include both tissue and blood (measuring all coding genes) across hereditary and acquired variants, resulting in the most comprehensive offering ever.”

“I am delighted to join Caris at such an exciting time,” said Weinstein. “In my 25-plus years, I’ve seen few companies with Caris’ potential to grow and to change the way we diagnose, monitor, treat and care for hundreds of thousands of cancer patients each year.”

In May, Caris announced an $830 million growth equity round at a $7.83 billion post-money valuation. The round was led by Sixth Street, a leading global investment firm making its third investment in Caris since 2018. Funds and accounts advised by T. Rowe Price Associates, Inc., Silver Lake, Fidelity Management & Research Company LLC, and Coatue were significant participants in the round. Additional investors included Columbia Threadneedle Investments, Canada Pension Plan Investment Board, Millennium Management, Neuberger Berman Funds, Highland Capital Management, Rock Springs Capital, OrbiMed, ClearBridge Investments, Tudor Investment Corporation, Eaton Vance Equity (Morgan Stanley), Pura Vida Investments and First Light Asset Management.

Mr. Weinstein brings to Caris more than 25 years of finance and life sciences experience. Prior to joining the Company, Weinstein served as Senior Vice President, Strategy at Medtronic and was a member of the Executive Committee. In that role he oversaw global strategy for the organization, including providing counsel and input on business development, capital deployment, and the overall strategic direction of each of Medtronic’s businesses. Prior to Medtronic, Weinstein was a Managing Director at JPMorgan Chase & Co., leading the firm’s healthcare group within equity research. Weinstein is a 14-time #1 ranked analyst in the annual surveys of both Institutional Investor and Greenwich Associates. In 2013, he was named to the Institutional Investor Hall of Fame. He is a summa cum laude graduate of Georgetown University and serves on the Board of Advisors for Georgetown’s McDonough School of Business.

Caris Life Sciences and National Cancer Center Japan Announce Exclusive Collaboration to Launch The SCRUM-Japan MONSTAR-SCREEN-2 Trial

May 20, 2021 Published by Roboticulized.com

Caris Life Sciences^®, a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine, announced today they have entered into an exclusive collaboration agreement with the National Cancer Center Japan (NCC) to provide Caris’ comprehensive molecular profiling in MONSTAR-SCREEN-2 of SCRUM-Japan, the largest cancer genomic screening consortium in Japan.

Under this agreement, patients will gain access to Caris Molecular Intelligence^®, a proprietary, comprehensive tumor profiling approach that assesses all 22,000 genes in both DNA and RNA, and proteins – unique to an individual’s cancer – to reveal a molecular blueprint in order to guide more precise and individualized treatment decisions. Additionally, Caris will provide access to its artificial intelligence (AI)-based predictors MI GPSai (Genomic Profiling Similarity) score and MI FOLFOXai. GPSai analyzes the patient’s tumor at the molecular level using both whole exome and whole transcriptome data to match the tumor’s molecular signature across 21 cancer types from the Caris database, to determine where the signature has been seen before. GPSai predicted the tumor type in the labeled data set with an accuracy of over 94% on 93% of cases, and with 97% accuracy when the top 2 predictions are considered. FOLFOXai is Caris’ AI-based predictor intended to gauge a metastatic colorectal cancer (mCRC) patient’s likelihood of benefit from first-line treatment FOLFOX followed by FOLFIRI, versus FOLFIRI followed by FOLFOX, both standard of care options. In December 2020, Caris published data in Clinical Cancer Research demonstrating 71% difference in overall survival for mCRC patients using its FOLFOXai predictor.

Launched in 2015, SCRUM-Japan is one of the world’s largest cancer initiatives, involving some 260 Japanese clinical facilities and 17 pharmaceutical companies. More than 17,000 patients are enrolled, with 2,000 more signed up annually. The multinational genomic screening program is designed to accelerate the development of innovative biomarker-driven precision medicine cancer therapies. By utilizing Caris’ next generation sequencing and AI-based predictors, participants will be matched to, and able to enroll in, targeted therapy clinical trials based on the data received from Caris’ molecular profile.

“Caris Life Sciences provides one of the most comprehensive tumor profiling offerings in the world, and we are proud to work with them as we prepare to launch the fourth phase of our program,” said Takayuki Yoshino, M.D., Ph.D., Head of Clinical Research Coordination Division & Director of Gastroenterology and Gastrointestinal Oncology at the National Cancer Center Hospital East. “This collaboration brings together the expertise, innovation and reach of Caris in the field of molecular profiling to our patients, and will allow treating physicians to make therapy-based decisions for their patients that ultimately help deliver better outcomes.”

“It is paramount that all patients and healthcare providers worldwide have access to precision medicine testing in order to guide treatment decisions and better inform patient care,” said W. Michael Korn, M.D., Chief Medical Officer at Caris Life Sciences. “Caris is pleased to partner with NCC to provide them with our industry-leading technology and suite of product offerings that will allow them to fully realize the potential of precision medicine in diagnostics, and set the stage for developing unique treatment approaches for patients as part of the groundbreaking MONSTAR-SCREEN-2 study.”

Sidney Kimmel Cancer Center at Jefferson Health Joins Caris Life Sciences’ Precision Oncology Alliance

May 15, 2021 Published by Roboticulized.com

Caris Life Sciences®, a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine, announced today that the Sidney Kimmel Cancer Center – Jefferson Health (SKCC) has joined Caris’ Precision Oncology Alliance (POA). The POA is a collaborative network of leading cancer centers that work together to advance comprehensive cancer profiling and establish standards of care for molecular testing in oncology through research focused on predictive and prognostic markers that improve the clinical outcomes of patients with cancer.

For nearly 25 years, SKCC, one of 71 National Cancer Institute (NCI)-designated cancer centers in the U.S., has provided oncology patients in the Greater Philadelphia region the latest developments in cancer research, technology and treatment. Using the most advanced treatment methods and technologies, their physicians and researchers help lead the world’s new cancer therapies.

“Our mission is to improve the lives of cancer patients and their families through compassion, innovation and breakthrough discoveries,” said Karen E. Knudsen, MBA, Ph.D., EVP of Oncology Services and Enterprise Director of SKCC. “We value the POA’s collaborative efforts in advancing precision medicine and look forward to contributing our team’s expertise in treatment methods and technologies that will further accelerate scientific breakthroughs to benefit patients worldwide.”

“Physicians and researchers at SKCC have helped transform scientific discoveries into improved cancer treatments for their patients,” said Chadi Nabhan, M.D., MBA, FACP, Chairman of the Caris Precision Oncology Alliance. “The POA welcomes their multidisciplinary experience in precision oncology to further our efforts in maximizing patient outcomes through advanced diagnostic testing and molecular insights. We look forward to collaborating with all of their investigators across all tumor types.”

The Caris Precision Oncology Alliance includes 50 cancer centers and academic institutions. These institutions have early access to the extensive database and artificial intelligence platform within Caris to establish evidence-based standards for cancer profiling and molecular testing in oncology. By leveraging the comprehensive genomic, transcriptomic and proteomic profiling available through the Caris Molecular Intelligence® platform, Caris seeks to provide this network with the ability to prioritize therapeutic options and determine which clinical trial opportunities may benefit their patients. POA members are also able to integrate with a growing portfolio of biomarker directed trials sponsored by biopharma. Additionally, as a member of the POA, institutions have access to Caris CODEai, the most comprehensive data solution in the industry with cancer treatment information and clinical outcomes data for over 244,000 patients covering over 1,000,000 data points per patient.

“The POA is excited to work with SKCC’s world-renowned research faculty to develop and test cancer treatments designed to transform care, by improving both survival and quality of life for patients with cancer around the world,” said Brian J. Brille, Vice Chairman of Caris Life Sciences.

Caris Life Sciences Announces Appointment of Joseph E. Gilliam to Board of Directors

April 29, 2021 Published by Roboticulized.com

Caris Life Sciences^®, a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine, announced the appointment of Joseph E. Gilliam to the Caris Board of Directors, effective April 12, 2021. Following the appointment of Mr. Gilliam, the Board will be comprised of 10 directors.

The Caris Life Sciences Board of Directors is responsible for the overall management of the company, including guiding strategies and monitoring company performance. The Caris Board is composed of a diverse group of leaders with distinct perspectives. Many of the current directors have held leadership roles at major domestic and international companies, academic and scientific organizations, and governmental agencies.

“We are pleased to welcome Joe to the Caris Board,” said David D. Halbert, Chairman and CEO of Caris Life Sciences. “Joe’s expertise in the life sciences industry, including the diagnostics and biotechnology sectors, will be helpful as we continue to advance precision medicine, accelerate corporate growth and pursue our vision to improve patient outcomes across all cancer types worldwide.”

“I am excited to join the Caris Board, and look forward to working alongside fellow board members and Caris’ management team,” said Mr. Gilliam. “I welcome the opportunity to contribute to Caris’ future growth and success as the company advances innovative technologies that revolutionize patient care.”

Mr. Gilliam is currently the Chief Financial Officer and Senior Vice President, Corporate Development at Glaukos Corporation, and has served in this role since May 2017. Prior to joining Glaukos, Mr. Gilliam held roles of increasing responsibility at JPMorgan over the course of a nearly 20-year financial services career. As a managing director in the healthcare investment banking group his experience spanned mergers and acquisitions, initial and follow-on public equity offerings, bank lending, bond offerings, and other transactions for a variety of companies in the life science tools, diagnostics, biotechnology and medical technology sectors. Mr. Gilliam’s prior experience includes positions at The Beacon Group (which was combined with JPMorgan and Chase Manhattan in 2001) and PricewaterhouseCoopers. Mr. Gilliam has a B.S. in accounting from the Kelly School of Business at Indiana University.

Tag: Caris Life Sciences

Caris’ Precision Oncology Alliance Welcomes Tampa General Hospital Cancer Institute

Caris Life Sciences Announces Appointment of Lloyd B. Minor to Board of Directors

Caris Life Sciences Announces Appointment of Mike Weinstein, Medical Technology Executive and Wall Street Veteran, as Chief Financial Officer

Caris Life Sciences and National Cancer Center Japan Announce Exclusive Collaboration to Launch The SCRUM-Japan MONSTAR-SCREEN-2 Trial

Sidney Kimmel Cancer Center at Jefferson Health Joins Caris Life Sciences’ Precision Oncology Alliance

Caris Life Sciences Announces Appointment of Joseph E. Gilliam to Board of Directors

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